Welcome to AM Technology

Manufacturers of Continuous Flow Reactors

Versatile. Productive. Efficient.

Coflore® Flow Reactors

The Realistic Alternative to Production-Scale Batch Chemical Manufacturing

AM Technology designs and manufactures continuous flow reactors and continuous flow chemical plants for the fine chemical and pharmaceutical industries.

Coflore active mixing technology unlocks the benefits of continuous flow to a wide-range of chemical processes from benchtop R&D to multi-tonne production plant.

Coflore Digital ACR Render

Laboratory Scale

100 mL Reactor Volume

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Pilot / Production Scale

10 L Reactor Volume

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Production Scale

100 L Reactor Volume

Grams / Kilograms

Kilograms / Tonnes

Tonnes / Kilotonnes

Coflore ACR  

An actively mixed, bench-top flow reactor, for developing and optimizing chemical processes in flow, or for when limited quantities of reactants or material are available or required. The Coflore ACR reactor process channel is divided into ten reactor cells, equivalent to ten CSTRs in series for plug flow.

For a 5-minute residence time, the Coflore ACR produces 1.2 L of material per hour.

Coflore ATR

A variable volume tubular flow reactor of up to eight reactor tubes in series for plug flow (0.35 to 10 L reactor volume). Directly scalable from the Coflore ACR, with active mixing technology, to produce material at pilot and production scales.

For a 5-minute residence time, the Coflore ATR produces 120 L of material per hour.

Coflore RTR

A 100 L production scale flow reactor, capable of processing countless reactor volumes without interruption. Such throughputs have the potential to produce many thousands of tons of material per year from a single reactor. The Coflore RTR operates as a ten-stage, actively mixed, and self-baffling plug flow reactor.

For a 5-minute residence time, the Coflore RTR produces 1,200 L of material per hour.

Coflore Digital ACR Render
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Why Manufacture in Coflore?

1. Improved Productive Capacity

Make more of what you need, in less time, in a smaller plant.

2. Improved Safety

Smaller working volumes and vastly improved heat transfer coefficients vs batch minimise risks of hazardous chemistry.

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3. Decrease Waste

Run reactions more concentrated to reduce solvent, improve reaction yields and product selectivity.

4. Scale Easily

Need more product? Run for longer. Avoid repeat batch cycles to fulfil larger demand.

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Have an existing chemical process that you would like to translate into flow? 

 

AM Technology offer a range of flow chemistry testing services at our head offices in Cheshire, UK. Our state-of-the-art laboratories are well-equipped with analytical and process equipment to test and assess customer-specific processes at both R&D and Pilot-Plant scale.

Our multidisciplinary team of experts will design, setup and carry out experiments according to your own specific requirements, with  submission of a full report of our findings on completion.

We can assist in converting existing batch processes into flow or alternatively work with your team to develop novel processes directly in flow.

Contact our technical team through our contact us form here, or by email at Info@amt.uk to find out more.

Our Coflore range of continuous flow reactors offers a clear pathway for scaling up chemical processes from R&D to multi-tonne scale.

Our in-house team consists of chemists, chemical, mechanical and electrical engineers as well as project managers who have years of experience taking chemical processes through from R&D to fully commissioned continuous flow chemical plants.

We can assist at every stage, and our engineering services are the perfect follow on from chemical feasibility / optimisation testing.

Contact our technical team through our contact us form here, or by email at Info@amt.uk to find out more.

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“One of today's most important tools for modernizing the pharmaceutical industry is a process known as continuous manufacturing”

Director of the FDA’s Center for Drug Evaluation and Research, Janet Woodcock M.D.