top of page

Plug Flow Reactors

What does Plug Flow mean?


Plug flow is an important characteristic of flow reactors, whereby any two molecules entering the reactor at time zero, exit at a similar time. The PFR reactor model provides an effective means of controlling reaction time while optimising the separation of reactants and products. Good plug flow is essential for good performance in all but a few applications and means that fluid travels through the reactor in a time-orderly way and without back-mixing. Reactors which employ plug flow chemistry are commonly referred to as plug flow reactors or PFR reactors.

Advantages of Plug Flow Chemistry

  • Efficient reaction time control: as products are removed from the reactor on formation

  • Efficient utilisation of reactor volume: since reacted material is not retained within the reactor

  • Optimum reaction yield and purity: due to efficient heat and mass transfer properties and removal of products on formation, reducing by-products

  • Low start-up and shutdown losses: due to the smaller volumes involved

Changing Concentration in Plug Flow Chemistry











Fluid going through a Plug Flow Reactor may be modelled as flowing through the reactor as a series of infinitely thin coherent 'plugs', each with a uniform composition, travelling in the axial direction of the reactor, with each plug having a different composition from the ones before and after it. 


The key assumption is that; as a plug flows through a plug flow reactor, the fluid is perfectly mixed in the radial direction but not in the axial direction (forwards or backward). Each plug of differential volume is considered as a separate entity, effectively an infinitesimally small continuous stirred tank reactor, limiting to zero volume.

Related Pages...

how plug flow chemistry works in a PFR

Schematic diagram of a plug flow reactor

plug flow reactor reactant and product diagram

Relationship between reactants and product within a plug flow reactor (PFR)

Useful External Links

Flow Chemistry (

“One of today's most important tools for modernizing the pharmaceutical industry is a process known as continuous manufacturing”

Director of the FDA’s Centre for Drug Evaluation and Research,

bottom of page